Magnetic hyperthermia equipment

This equipment enables experiments involving the excitation of magnetic nanoparticles using alternating magnetic fields, causing the particles to generate heat. The system makes it possible to work with nanoparticles in inert samples, using a calorimeter to measure the specific absorption rate (SAR) of energy, or energy which the magnetic field transmits to the particles and which induces an increase in temperature, from which the SAR may be deduced. It also makes it possible to work with samples at a fixed external temperature, such that the heat produced only increases the temperature locally. In that case, experiments can be conducted with cell cultures and small animals (mice) or with samples of other kinds. The equipment can generate excitation with four non-sinusoidal waveforms, with a constant and controlled gradient from triangular to almost square, and a fifth sinusoidal signal in the range from 100 kHz to 1 MHz and with a peak intensity of up to 10 mT. The system has a user interface that displays the current and magnetic field in real time. The electromagnetic field is generated using a coil, inside which different sample holders can be placed, as required, which ensure that the sample is always insulated from the heat generated by the coil itself.